2165. Risk Factors for CPE Colonization in Household Contacts of CPE Colonized/Infected Patients
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چکیده
منابع مشابه
Clostridium Perfringens Enterotoxin (CPE) and CPE-Binding Domain (c-CPE) for the Detection and Treatment of Gynecologic Cancers
Clostridium perfringens enterotoxin (CPE) is a three-domain polypeptide, which binds to Claudin-3 and Claudin-4 with high affinity. Because these receptors are highly differentially expressed in many human tumors, claudin-3 and claudin-4 may provide an efficient molecular tool to specifically identify and target biologically aggressive human cancer cells for CPE-specific binding and cytolysis. ...
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Clostridium perfringens enterotoxin (CPE) causes the symptoms of a very common food poisoning. To assess whether CPE-induced cytotoxicity is necessary for enterotoxicity, a rabbit ileal loop model was used to compare the in vivo effects of native CPE or recombinant CPE (rCPE), both of which are cytotoxic, with those of the noncytotoxic rCPE variants rCPE D48A and rCPE(168-319). Both CPE and rCP...
متن کاملNetwork Model of the CPE
Analysis of fractal systems (i.e. systems described by fractional differential equations) necessitates to create an electrical analog model of a crucial subsystem called Constant Phase Element (CPE). The paper describes a possible realization of such a model that is quite simple and in spite of its simplicity makes it possible to simulate the properties of ideal CPEs. The paper also deals with ...
متن کاملOrganization of the cpe Locus in CPE-Positive Clostridium perfringens Type C and D Isolates
Clostridium perfringens enterotoxin (encoded by the cpe gene) contributes to several important human, and possibly veterinary, enteric diseases. The current study investigated whether cpe locus organization in type C or D isolates resembles one of the three (one chromosomal and two plasmid-borne) cpe loci commonly found amongst type A isolates. Multiplex PCR assays capable of detecting sequence...
متن کاملIdentification of peptides from brain and pituitary of Cpe(fat)/Cpe(fat) mice.
Cpe(fat)/Cpe(fat) mice have a naturally occurring point mutation within the carboxypeptidase E gene that inactivates this enzyme, leading to an accumulation of many neuroendocrine peptides containing C-terminal basic residues. These processing intermediates can be readily purified on an anhydrotrypsin affinity resin. Using MS to obtain molecular mass and partial sequence information, more than ...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2018
ISSN: 2328-8957
DOI: 10.1093/ofid/ofy210.1821